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153次一、 核心優(yōu)勢：創(chuàng)新化學與生物學的交叉應用
1. 特色分子實體：公司的主要優(yōu)勢在于設計和合成一系列具有新穎化學結構的、有生物活性的小分子化合物。這些分子通常靶向代謝、表觀遺傳、免疫調控等現(xiàn)代生物醫(yī)學研究中的熱門通路。
2. 工具化合物聚焦：不僅提供化合物本身，更注重開發(fā)能用于靶點驗證和功能研究的“工具化合物"。這些分子常具有較好的選擇性，有助于在細胞和動物模型中解析特定靶點的生物學功能。
3. 轉化研究導向：其產(chǎn)品開發(fā)思路與藥物發(fā)現(xiàn)的前期階段（靶點驗證、先導化合物篩選）緊密銜接。提供的分子常被學術機構和工業(yè)界的研究人員用于概念驗證性實驗，為后續(xù)開發(fā)潛在的治療方法提供早期數(shù)據(jù)支持。
4. 專業(yè)合作網(wǎng)絡：公司通常與學術界的前沿研究團隊保持合作，基于新興的生物學發(fā)現(xiàn)來共同設計新的化合物，使其產(chǎn)品線能夠觸及較為前沿的研究方向。
二、 解決實驗中的哪些挑戰(zhàn)？
在探索復雜生物機制和尋找新藥靶點的過程中，研究人員常面臨工具和手段的局限。MoraDec 提供的活性分子旨在應對部分挑戰(zhàn)。
1. 新靶點的功能驗證：當通過基因組學、蛋白質組學等方法發(fā)現(xiàn)一個潛在新靶點后，如何快速驗證其在疾病中的功能是關鍵。公司提供的選擇性小分子抑制劑或激活劑，可作為藥理學工具，快速評估調控該靶點產(chǎn)生的表型效應，加速靶點驗證流程。
2. 信號通路的精細剖析：許多疾病相關通路存在復雜的互作網(wǎng)絡。利用選擇性較高的工具化合物，可以相對特異性地干擾通路中的某個節(jié)點（如特定的激酶、代謝酶），有助于更清晰地繪制信號傳遞圖譜，明確關鍵環(huán)節(jié)。
3. 克服傳統(tǒng)工具的不足：對于一些靶點，可能缺乏商品化的、性能良好的抗體用于功能實驗，或者基于RNA干擾（RNAi）的技術存在脫靶效應和敲低的問題。小分子工具提供了一種互補的、可逆的、常可快速起效的研究手段。
4. 探索“不可成藥"靶點：公司關注的部分化學系列，旨在針對傳統(tǒng)上被認為難以用小分子干預的靶點類別（如某些蛋白質-蛋白質相互作用界面），為相關研究領域提供了新的探針和可能性。
三、 產(chǎn)品選擇常見疑問與解答
在考慮將MoraDec的化合物納入您的研究時，以下信息或許有幫助：
問： 這些化合物主要適用于哪個研究階段？
答： 這些化合物主要適用于基礎研究、靶點發(fā)現(xiàn)與驗證、臨床前研究等階段。它們是強有力的研究工具，用于在細胞和動物模型中探索生物學機制和概念，但通常尚未進行完整的藥物開發(fā)流程，不作為治療藥物直接使用。
問： 如何了解某個化合物的選擇性和脫靶效應？
答： 公司通常會提供其核心化合物在公開或內(nèi)部進行的部分激酶譜、細胞活性面板測試數(shù)據(jù)。研究人員應仔細查閱產(chǎn)品資料中提供的選擇性數(shù)據(jù)。但必須注意，任何小分子的選擇性都是相對的。在用于關鍵結論性實驗前，結合基因敲除/敲低等遺傳學方法進行交叉驗證，是嚴謹?shù)难芯繉嵺`。
問： 化合物的溶解性和穩(wěn)定性如何？如何進行儲存和配制？
答： 這是使用活性小分子的重要環(huán)節(jié)。每款產(chǎn)品都應提供建議的儲存條件（如-20°C干燥避光）、推薦溶劑（如DMSO）和配制方法。建議使用時，嚴格按照說明書操作，并注意分裝保存，避免反復凍融，以保持化合物穩(wěn)定性。對于難溶化合物，可能需要嘗試不同的助溶策略。
問： 在動物實驗中，有推薦的給藥方案參考嗎？
答： 對于部分經(jīng)過體內(nèi)測試的化合物，資料中可能會提供已在特定動物模型（如小鼠）中驗證過的給藥途徑、劑量范圍和初步藥代動力學參數(shù)。這些數(shù)據(jù)可作為您實驗設計的重要參考起點，但最終方案需根據(jù)您自身的模型和實驗目的進行優(yōu)化和驗證。
問： 可以獲取用于初步實驗的樣品嗎？
答： 許多研究用化合物供應商，包括MoraDec，通常有針對學術研究人員的樣品申請或小規(guī)格包裝購買計劃。特別是對于新發(fā)表或受關注的化合物，建議通過其網(wǎng)站或授權代理商渠道，查詢具體的樣品申請政策。
問： 如果我對某個靶點感興趣，但目錄中沒有相應產(chǎn)品，可以咨詢嗎？
答： 可以。鑒于公司的業(yè)務聚焦于新化合物發(fā)現(xiàn)，如果您的研究靶點與其專注的領域（如代謝、表觀遺傳等）相關，可以嘗試聯(lián)系其科學團隊進行咨詢。他們可能會分享該靶點相關的最新研究進展，或在研管線信息。
關鍵詞：MoraDec、小分子化合物、工具化合物、靶點驗證、代謝疾病研究、免疫學研究、激酶抑制劑、表觀遺傳抑制劑、先導化合物、化學探針、藥物研發(fā)工具、信號通路研究、不可成藥靶點、細胞活性分子、研究用化學品、生物活性分子、創(chuàng)新療法研究、體外研究工具、轉化醫(yī)學研究、機制研究
特別告知：為保證產(chǎn)品質量與良好性能，所以在購買相應產(chǎn)品的同時我司會收取一定量的運輸費用！！！本次報價有效時間為2026年4月16日---2026年12月20日。
（*此為部分產(chǎn)品價格,完整價格請下載文件)
貨號 | 品名 | 規(guī)格 | 價格 | 品牌 |
AH-101AF-50 | IgGs Anti-Human IgG Fc-MMAF Antibody with Non-Cleavable Linker 50µg | 50ug | 7992.00 | moradec |
AH-101AF-20 | IgGs Anti-Human IgG Fc-MMAF Antibody with Non-Cleavable Linker 20µg | 20ug | 3996.00 | moradec |
AH-102AF-50 | IgGs Anti-Human IgG Fc-MMAF Antibody with Cleavable Linker 50µg | 50ug | 7992.00 | moradec |
AH-102AF-20 | IgGs Anti-Human IgG Fc-MMAF Antibody with Cleavable Linker 20µg | 20ug | 3996.00 | moradec |
AH-102AE-50 | IgGs Anti-Human IgG Fc-MMAE Antibody with Cleavable Linker 50µg | 50ug | 7992.00 | moradec |
AH-102AE-20 | IgGs Anti-Human IgG Fc-MMAE Antibody with Cleavable Linker 20µg | 20ug | 3996.00 | moradec |
AH-102DD-50 | IgGs Anti-Human IgG Fc-Duocarmycin DM Antibody with Cleavable Linker 50µg | 50ug | 7992.00 | moradec |
AH-102DD-20 | IgGs Anti-Human IgG Fc-Duocarmycin DM Antibody with Cleavable Linker 20µg | 20ug | 3996.00 | moradec |
AH-102PN-50 | IgGs Anti-Human IgG Fc-PNU159682 Antibody with Cleavable Linker 50µg | 50ug | 7992.00 | moradec |
AH-102PN-20 | IgGs Anti-Human IgG Fc-PNU159682 Antibody with Cleavable Linker 20µg | 20ug | 3996.00 | moradec |
AH-103D1-50 | IgGs Anti-Human IgG Fc-DM1 Antibody with Non-Cleavable Linker 50µg | 50ug | 7992.00 | moradec |
AH-103D1-20 | IgGs Anti-Human IgG Fc-DM1 Antibody with Non-Cleavable Linker 20µg | 20ug | 3996.00 | moradec |
AH-106PB-50 | IgGs Anti-Human IgG Fc-PBD Antibody with Cleavable Linker 50µg | 50ug | 7992.00 | moradec |
AH-106PB-20 | IgGs Anti-Human IgG Fc-PBD Antibody with Cleavable Linker 20µg | 20ug | 3996.00 | moradec |
AH-107DX-50 | IgGs Anti-human IgG Fc-DX8951 Antibody with Cleavable Linker 50µg | 50ug | 7992.00 | moradec |
AH-107DX-20 | IgGs Anti-human IgG Fc-DX8951 Antibody with Cleavable Linker 20µg | 20ug | 3996.00 | moradec |
AH-201AF-50 | Fab Anti-Human IgG Fc-MMAF Antibody with Non-Cleavable Linker 50µg | 50ug | 10512.00 | moradec |
AH-201AF-20 | Fab Anti-Human IgG Fc-MMAF Antibody with Non-Cleavable Linker 20µg | 20ug | 5256.00 | moradec |
AH-202AF-50 | Fab Anti-Human IgG Fc-MMAF Antibody with Cleavable Linker 50µg | 50ug | 10512.00 | moradec |
AH-202AF-20 | Fab Anti-Human IgG Fc-MMAF Antibody with Cleavable Linker 20µg | 20ug | 5256.00 | moradec |
AH-202AE-50 | Fab Anti-Human IgG Fc-MMAE Antibody with Cleavable Linker 50µg | 50ug | 10512.00 | moradec |
AH-202AE-20 | Fab Anti-Human IgG Fc-MMAE Antibody with Cleavable Linker 20µg | 20ug | 5256.00 | moradec |
AH-202DD-50 | Fab Anti-Human IgG Fc-Duocarmycin DM Antibody with Cleavable Linker 50µg | 50ug | 10512.00 | moradec |
AH-202DD-20 | Fab Anti-Human IgG Fc-Duocarmycin DM Antibody with Cleavable Linker 20µg | 20ug | 5256.00 | moradec |
AH-202PN-50 | Fab Anti-Human IgG Fc-PNU159682 Antibody with Cleavable Linker 50µg | 50ug | 10512.00 | moradec |
AH-202PN-20 | Fab Anti-Human IgG Fc-PNU159682 Antibody with Cleavable Linker 20µg | 20ug | 5256.00 | moradec |
AH-203D1-50 | Fab Anti-Human IgG Fc-DM1 Antibody with Non-Cleavable Linker 50µg | 50ug | 10512.00 | moradec |
AH-203D1-20 | Fab Anti-Human IgG Fc-DM1 Antibody with Non-Cleavable Linker 20µg | 20ug | 5256.00 | moradec |
AH-205AM-50 | Fab Anti-Human IgG Fc-Amanitin Antibody with Non-Cleavable Linker 50µg | 50ug | 10512.00 | moradec |
AH-205AM-20 | Fab Anti-Human IgG Fc-Amanitin Antibody with Non-Cleavable Linker 20µg | 20ug | 5256.00 | moradec |
AH-207DX-50 | Fab Anti-human IgG Fc-DX8951 Antibody with Cleavable Linker 50µg | 50ug | 10512.00 | moradec |
AH-207DX-20 | Fab Anti-human IgG Fc-DX8951 Antibody with Cleavable Linker 20µg | 20ug | 5256.00 | moradec |
AH-209AE-50 | Fab Anti-human IgG Fc-MMAE Antibody with Glucuronic Acid Linker 50µg | 50ug | 10512.00 | moradec |
AH-209AE-20 | Fab Anti-human IgG Fc-MMAE Antibody with Glucuronic Acid Linker 20µg | 20ug | 5256.00 | moradec |
AH-209EX-50 | Fab Anti-Human IgG Fc-Extecan Antibody with Glucuronic Acid Linker 50µg | 50ug | 10512.00 | moradec |
AH-209EX-20 | Fab Anti-Human IgG Fc-Extecan Antibody with Glucuronic Acid Linker 20µg | 20ug | 5256.00 | moradec |
AH-121AF-50 | IgGs Anti-Human IgG Fab-MMAF Antibody with Nonceavable Linker 50µg | 50ug | 8820.00 | moradec |
AH-121AF-20 | IgGs Anti-Human IgG Fab-MMAF Antibody with Nonceavable Linker 20µg | 20ug | 4410.00 | moradec |
AH-122AF-50 | IgGs Anti-Human IgG Fab-MMAF Antibody with Cleavable Linker 50µg | 50ug | 8820.00 | moradec |
AH-122AF-20 | IgGs Anti-Human IgG Fab-MMAF Antibody with Cleavable Linker 20µg | 20ug | 4410.00 | moradec |
AH-122AE-50 | IgGs Anti-Human IgG Fab-MMAE Antibody with Cleavable Linker 50µg | 50ug | 8820.00 | moradec |
AH-122AE-20 | IgGs Anti-Human IgG Fab-MMAE Antibody with Cleavable Linker 20µg | 20ug | 4410.00 | moradec |
AH-123D1-50 | IgGs Anti-Human IgG Fab-DM1 Antibody with Non-Cleavable Linker 50µg | 50ug | 8820.00 | moradec |
AH-123D1-20 | IgGs Anti-Human IgG Fab-DM1 Antibody with Non-Cleavable Linker 20µg | 20ug | 4410.00 | moradec |
AM-101AF-50 | IgGs Anti-Mouse IgG Fc-MMAF Antibody with Non-Cleavable Linker 50µg | 50ug | 9036.00 | moradec |
AM-101AF-20 | IgGs Anti-Mouse IgG Fc-MMAF Antibody with Non-Cleavable Linker 20µg | 20ug | 4518.00 | moradec |
AM-102AF-50 | IgGs Anti-Mouse IgG Fc-MMAF Antibody with Cleavable Linker 50µg | 50ug | 9036.00 | moradec |
AM-102AF-20 | IgGs Anti-Mouse IgG Fc-MMAF Antibody with Cleavable Linker 20µg | 20ug | 4518.00 | moradec |
AM-102AE-50 | IgGs Anti-Mouse IgG Fc-MMAE Antibody with Cleavable Linker 50µg | 50ug | 9036.00 | moradec |
AM-102AE-20 | IgGs Anti-Mouse IgG Fc-MMAE Antibody with Cleavable Linker 20µg | 20ug | 4518.00 | moradec |
AM-102DD-50 | IgGs Anti-Mouse IgG Fc-Duocarmycin DM Antibody with Cleavable Linker 50µg | 50ug | 9036.00 | moradec |
AM-102DD-20 | IgGs Anti-Mouse IgG Fc-Duocarmycin DM Antibody with Cleavable Linker 20µg | 20ug | 4518.00 | moradec |
AM-102PN-50 | IgGs Anti-Mouse IgG Fc-PNU159682 Antibody with Cleavable Linker 50µg | 50ug | 9036.00 | moradec |
AM-102PN-20 | IgGs Anti-Mouse IgG Fc-PNU159682 Antibody with Cleavable Linker 20µg | 20ug | 4518.00 | moradec |
AM-103D1-50 | IgGs Anti-Mouse IgG Fc-DM1 Antibody with Non-Cleavable Linker 50µg | 50ug | 9036.00 | moradec |
AM-103D1-20 | IgGs Anti-Mouse IgG Fc-DM1 Antibody with Non-Cleavable Linker 20µg | 20ug | 4518.00 | moradec |
AM-106PB-50 | IgGs Anti-Mouse IgG Fc-PBD Antibody with Cleavable Linker 50µg | 50ug | 9036.00 | moradec |
AM-106PB-20 | IgGs Anti-Mouse IgG Fc-PBD Antibody with Cleavable Linker 20µg | 20ug | 4518.00 | moradec |
AM-107DX-50 | IgGs Anti-Mouse IgG Fc-DX8951 Antibody with Cleavable Linker 50µg | 50ug | 9036.00 | moradec |
AM-107DX-20 | IgGs Anti-Mouse IgG Fc-DX8951 Antibody with Cleavable Linker 20µg | 20ug | 4518.00 | moradec |
AM-201AF-50 | Fab Anti-Mouse IgG Fc-MMAF Antibody with Non-Cleavable Linker 50µg | 50ug | 11988.00 | moradec |
AM-201AF-20 | Fab Anti-Mouse IgG Fc-MMAF Antibody with Non-Cleavable Linker 20µg | 20ug | 5994.00 | moradec |
AM-202AF-50 | Fab Anti-Mouse IgG Fc-MMAF Antibody with Cleavable Linker 50µg | 50ug | 11988.00 | moradec |
AM-202AF-20 | Fab Anti-Mouse IgG Fc-MMAF Antibody with Cleavable Linker 20µg | 20ug | 5994.00 | moradec |
AM-202AE-50 | Fab Anti-Mouse IgG Fc-MMAE Antibody with Cleavable Linker 50µg | 50ug | 11988.00 | moradec |
AM-202AE-20 | Fab Anti-Mouse IgG Fc-MMAE Antibody with Cleavable Linker 20µg | 20ug | 5994.00 | moradec |
AM-202DD-50 | Fab Anti-Mouse IgG Fc-duocarmycin DM Antibody with Cleavable Linker 50µg | 50ug | 11988.00 | moradec |
AM-202DD-20 | Fab Anti-Mouse IgG Fc-duocarmycin DM Antibody with Cleavable Linker 20µg | 20ug | 5994.00 | moradec |
AM-203D1-50 | Fab Anti-Mouse IgG Fc-DM1 Antibody with Noncleavable Linker 50µg | 50ug | 11988.00 | moradec |
AM-203D1-20 | Fab Anti-Mouse IgG Fc-DM1 Antibody with Noncleavable Linker 20µg | 20ug | 5994.00 | moradec |
AO-101AF-50 | IgGs Anti-Rabbit IgG Fc-MMAF Antibody with Non-Cleavable Linker 50µg | 50ug | 9828.00 | moradec |
AO-101AF-20 | IgGs Anti-Rabbit IgG Fc-MMAF Antibody with Non-Cleavable Linker 20µg | 20ug | 4914.00 | moradec |
AO-201AF-50 | Fab Anti-Rabbit IgG Fc-MMAF Antibody with Non-Cleavable Linker 50µg | 50ug | 12816.00 | moradec |
AO-201AF-20 | Fab Anti-Rabbit IgG Fc-MMAF Antibody with Non-Cleavable Linker 20µg | 20ug | 6408.00 | moradec |
AO-111AF-50 | IgGs Anti-Rabbit IgG(H+L)-MMAF Antibody with Non-Cleavable Linker 50µg | 50ug | 9828.00 | moradec |
AO-111AF-20 | IgGs Anti-Rabbit IgG(H+L)-MMAF Antibody with Non-Cleavable Linker 20µg | 20ug | 4914.00 | moradec |
AO-112AF-50 | IgGs Anti-Rabbit IgG(H+L)-MMAF Antibody with Cleavable Linker 50µg | 50ug | 9828.00 | moradec |
AO-112AF-20 | IgGs Anti-Rabbit IgG(H+L)-MMAF Antibody with Cleavable Linker 20µg | 20ug | 4914.00 | moradec |
AO-112AE-50 | IgGs Anti-Rabbit IgG(H+L)-MMAE Antibody with Cleavable Linker 50µg | 50ug | 9828.00 | moradec |
AO-112AE-20 | IgGs Anti-Rabbit IgG(H+L)-MMAE Antibody with Cleavable Linker 20µg | 20ug | 4914.00 | moradec |
AO-116PB-50 | IgGs Anti-Rabbit IgG(H+L)-PBD Antibody with Cleavable Linker 50µg | 50ug | 9828.00 | moradec |
AO-116PB-20 | IgGs Anti-Rabbit IgG(H+L)-PBD Antibody with Cleavable Linker 20µg | 20ug | 4914.00 | moradec |
AO-211AF-50 | Fab Anti-Rabbit IgG(H+L)-MMAF Antibody with Non-Cleavable Linker 50µg | 50ug | 12816.00 | moradec |
AO-211AF-20 | Fab Anti-Rabbit IgG(H+L)-MMAF Antibody with Non-Cleavable Linker 20µg | 20ug | 6408.00 | moradec |
AO-212AF-50 | Fab Anti-Rabbit IgG(H+L)-MMAF Antibody with Cleavable Linker 50µg | 50ug | 12816.00 | moradec |
AO-212AF-20 | Fab Anti-Rabbit IgG(H+L)-MMAF Antibody with Cleavable Linker 20µg | 20ug | 6408.00 | moradec |
AO-202DD-50 | Fab Anti-Rabbit IgG Fc-Duocarmycin DM Antibody with Cleavable Linker 50µg | 50ug | 12816.00 | moradec |
AO-202DD-20 | Fab Anti-Rabbit IgG Dc-Duocarmycin DM Antibody with Cleavable Linker 20µg | 20ug | 6408.00 | moradec |
AR-201AF-50 | Fab Anti-Rat IgG Fc-MMAF Antibody with Non-Cleavable Linker 50µg | 50ug | 12816.00 | moradec |
AR-201AF-20 | Fab Anti-Rat IgG Fc-MMAF Antibody with Non-Cleavable Linker 20µg | 20ug | 6408.00 | moradec |
AR-202AF-50 | Fab Anti-Rat IgG Fc-MMAF Antibody with Cleavable Linker 50µg | 50ug | 12816.00 | moradec |
AR-202AF-20 | Fab Anti-Rat IgG Fc-MMAF Antibody with Cleavable Linker 20µg | 20ug | 6408.00 | moradec |
AR-202AE-50 | Fab Anti-Rat IgG Fc-MMAE Antibody with Cleavable Linker 50µg | 50ug | 12816.00 | moradec |
AR-202AE-20 | Fab Anti-Rat IgG Fc-MMAE Antibody with Cleavable Linker 20µg | 20ug | 6408.00 | moradec |
AR-202DD-50 | Fab Anti-Rat IgG Fc-Duocarmycin DM Antibody with Cleavable Linker 50µg | 50ug | 12816.00 | moradec |
AR-202DD-20 | Fab Anti-Rat IgG Fc-Duocarmycin DM Antibody with Cleavable Linker 20µg | 20ug | 6408.00 | moradec |
AR-211AF-50 | Fab Anti-Rat IgG(H+L)-MMAF Antibody with Non-Cleavable Linker 50µg | 50ug | 12816.00 | moradec |
AR-211AF-20 | Fab Anti-Rat IgG(H+L)-MMAF Antibody with Non-Cleavable Linker 20µg | 20ug | 6408.00 | moradec |
AR-212AF-50 | Fab Anti-Rat IgG(H+L)-MMAF Antibody with Cleavable Linker 50µg | 50ug | 12816.00 | moradec |
AR-212AF-20 | Fab Anti-Rat IgG(H+L)-MMAF Antibody with Cleavable Linker 20µg | 20ug | 6408.00 | moradec |
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