CD8 is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. CD8 acts as a co-receptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional CD8 is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.
CD8 identifies cytotoxic/suppressor t-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of t-cell mediated killing. CD8 alpha chains binds to class-I MHC molecules alpha-3 domains.

Clone

hCD8.

Immunogen

Purified human PBL CD8+ T cells.

Ig Subclass

Mouse IgG2a.

Purification Method

Ion exchange column.

Protein concentration

1mg/ml in PBS (after reconstitution).

Storage Procedures

Lyophilized: store at 4oC. After reconstitution, if not intended for use within a month, aliquot and store at -20oC.

Reconstitution

Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.

Antibody Properties

Staining antibody, weakly cytotoxic. For staining, use 10µl/1,000,000 cells. Titer for cytotoxicity should be determined by the investigator.

Available Conjugates

This antibody is also available conjugated to biotin.

Usage

Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Related Products

» CD8 Antibody

» CD8 Antibody, Biotin

» CD8 Antibody, FITC

» CD8 biotin Antibody

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PARK7 ant-317 Mouse Anti Human Parkinson Disease Protein 7

PCNA ant-341 Mouse Anti Human Proliferating Cell Nuclear Antigen

PDCD1 ant-417 Mouse Anti Human Programmed Cell Death 1

PDCD12 ant-457 Mouse Anti Human Programmed Cell Death 12

PDCD4 ant-338 Mouse Anti Human Programmed Cell Death 4

PDPN ant-343 Mouse Anti Human Podoplanin

PDX-1 ant-162 Polyclonal Rabbit Anti Pancreas Duodenum Homeobox-1

PGP9.5 ant-335 Mouse Anti Human PGP9.5

PLP ant-200 Mouse Anti Porteolipid Protein of Myelin

PSMA ant-450 Mouse Anti Human Prostate Specific Cancer Antigen

RAB5A ant-337 Mouse Anti Human RAB5A

Rac2 ant-067 Mouse Anti Human Ras-Related C3 Botulinum Toxin Substrate 2

RASSF1A ant-400 Mouse Anti Human Ras association domain-containing protein 1

REXO1 ant-413 Mouse Anti Human RNA exonuclease 1 homolog

SERPINB5 ant-364 Mouse Anti Human Serpin Peptidase Inhibitor, Clade B Member 5

SNAP25 ant-336 Mouse Anti Human Synaptosomal-associated protein 25

SNCA ant-315 Mouse Anti Human Alpha-Synuclein

SNCB ant-454 Polyclonal Rabbit Anti Human Beta-Synuclein

SNCG ant-455 Polyclonal Rabbit Anti Human Gamma-Synuclein

Streptavidin ant-345 Mouse Anti Streptavidin

SUMO2/3 ant-016 Mouse Anti Human Small Ubiquitin-Related Modifier 2/3

TARDBP ant-420 Mouse Anti Human TAR DNA-binding protein 43

TBCA ant-362 Mouse Anti Human Tubulin Folding Cofactor A

Tetanus ant-195 Recombinant Anti-Tetanus Toxoid scFv

TGFBI ant-349 Mouse Anti Human Transforming Growth Factor Beta Induced

TLR2 ant-408 Mouse Anti Human Toll-like receptor 2

TLR7 ant-403 Mouse Anti Human Toll-like receptor 7

TMEFF2 ant-428 Mouse Anti Human Tomoregulin-2

TOLLIP ant-430 Mouse Anti Human Toll-interacting protein

TPD52L1 ant-302 Mouse Anti Human Tumor Protein D52 L1

TREM2 ant-429 Mouse Anti Human Triggering receptor expressed on myeloid cells 2

TTR ant-003 Mouse Anti Human Transthyretin

TUBB2b ant-019 Mouse Anti Human Tubulin beta-2B chain

VAMP2 ant-334 Mouse Anti Human Synaptobrevin-2

VAMP3 ant-352 Mouse Anti Human Synaptobrevin-3

VHL ant-316 Mouse Anti Human Von Hippel-Lindau Protein

Vimentin ant-245 Mouse Anti Human Vimentin

Vimentin Biotin ant-246 Mouse Anti Human Vimentin Biotinylated

Vimentin FITC ant-247 Mouse Anti Human Vimentin FITC

WNT3A ant-431 Mouse Anti Human Protein Wnt-3a

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Anti-Human CD3 SAFIRE Purified¥3245
Anti-ATP5O 4C11C10D12 antibody （ab110276）抗ATP5O 4C面議
PD-L1 RUO 濃縮液 IHC抗體，克隆編號 22C3面議
Dako 22C3 PD-L1科研抗體，腫瘤細胞檢測面議
Dako PD-L1 IHC 22C3單克隆抗體面議
Dako M3653單克隆抗體 PD-L1面議
DAKO/安捷倫 IHC抗體克隆編號 22C3面議
DAKO/agilent PD-L1單克隆抗體面議
Dako單克隆鼠抗人PD-L1，克隆編號 22C3面議
CD28 CD3 PeproTech功能性抗體面議

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