Catalogue Number	ANT-421
Synonyms	Amyloid beta A4 protein, Alzheimer disease amyloid protein, ABPP, APPI, APP, PreA4, Cerebral vascular amyloid peptide, CVAP, Protease nexin-II, PN-II, A4, AD1, AAA, PN2, ABETA, CTFgamma.
Type	Mouse Anti Human Monoclonal.
Introduction	APP is a cell surface receptor and transmembrane precursor protein which is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in the APP gene are implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy).
Clone	PJ4H9AT.
Immunogen	Anti-human APP mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human APP amino acids 18-289 purified from E. coli.
Ig Subclass	Mouse IgG2b heavy chain and κ light chain.
Purification Method	APP antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Protein formulation	1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.
Storage Procedures	For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.
Stability / Shelf Life	12 months at -20°C. 1 month at 4°C.
Applications	APP antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:1,000 ~ 2,000. Recommended starting dilution is 1:1,000.
Usage	ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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p53 ant-192 Recombinant Anti p53 scFv

p53 ant-228 Mouse Anti p53

PAP-1 ant-218 Polyclonal Rabbit Anti Human Pancreatitis-associated protein

PARK7 ant-317 Mouse Anti Human Parkinson Disease Protein 7

PCNA ant-341 Mouse Anti Human Proliferating Cell Nuclear Antigen

PDCD1 ant-417 Mouse Anti Human Programmed Cell Death 1

PDCD12 ant-457 Mouse Anti Human Programmed Cell Death 12

PDCD4 ant-338 Mouse Anti Human Programmed Cell Death 4

PDPN ant-343 Mouse Anti Human Podoplanin

PDX-1 ant-162 Polyclonal Rabbit Anti Pancreas Duodenum Homeobox-1

PGP9.5 ant-335 Mouse Anti Human PGP9.5

PLP ant-200 Mouse Anti Porteolipid Protein of Myelin

PSMA ant-450 Mouse Anti Human Prostate Specific Cancer Antigen

RAB5A ant-337 Mouse Anti Human RAB5A

Rac2 ant-067 Mouse Anti Human Ras-Related C3 Botulinum Toxin Substrate 2

RASSF1A ant-400 Mouse Anti Human Ras association domain-containing protein 1

REXO1 ant-413 Mouse Anti Human RNA exonuclease 1 homolog

SERPINB5 ant-364 Mouse Anti Human Serpin Peptidase Inhibitor, Clade B Member 5

SNAP25 ant-336 Mouse Anti Human Synaptosomal-associated protein 25

SNCA ant-315 Mouse Anti Human Alpha-Synuclein

SNCB ant-454 Polyclonal Rabbit Anti Human Beta-Synuclein

SNCG ant-455 Polyclonal Rabbit Anti Human Gamma-Synuclein

Streptavidin ant-345 Mouse Anti Streptavidin

SUMO2/3 ant-016 Mouse Anti Human Small Ubiquitin-Related Modifier 2/3

TARDBP ant-420 Mouse Anti Human TAR DNA-binding protein 43

TBCA ant-362 Mouse Anti Human Tubulin Folding Cofactor A

Tetanus ant-195 Recombinant Anti-Tetanus Toxoid scFv

TGFBI ant-349 Mouse Anti Human Transforming Growth Factor Beta Induced

TLR2 ant-408 Mouse Anti Human Toll-like receptor 2

TLR7 ant-403 Mouse Anti Human Toll-like receptor 7

TMEFF2 ant-428 Mouse Anti Human Tomoregulin-2

TOLLIP ant-430 Mouse Anti Human Toll-interacting protein

TPD52L1 ant-302 Mouse Anti Human Tumor Protein D52 L1

TREM2 ant-429 Mouse Anti Human Triggering receptor expressed on myeloid cells 2

TTR ant-003 Mouse Anti Human Transthyretin

TUBB2b ant-019 Mouse Anti Human Tubulin beta-2B chain

VAMP2 ant-334 Mouse Anti Human Synaptobrevin-2

VAMP3 ant-352 Mouse Anti Human Synaptobrevin-3

VHL ant-316 Mouse Anti Human Von Hippel-Lindau Protein

Vimentin ant-245 Mouse Anti Human Vimentin

Vimentin Biotin ant-246 Mouse Anti Human Vimentin Biotinylated

Vimentin FITC ant-247 Mouse Anti Human Vimentin FITC

WNT3A ant-431 Mouse Anti Human Protein Wnt-3a

重慶市華雅干細胞技術有限公司 ：2233895903

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