Cytokeratin LMW(低分子量細(xì)胞角蛋白)

廣州健侖生物科技有限公司

該抗體可識別56.5、50.48和40KDa的酸性細(xì)胞角蛋白。與波形蛋白、結(jié)蛋白、膠質(zhì)纖維性蛋白和神經(jīng)絲蛋白等無交叉反應(yīng)。用于標(biāo)記上皮及上皮來源的腫瘤，特別對研究轉(zhuǎn)移性腫瘤是否為上皮源性有一定意義。

革蘭氏染色反應(yīng)是細(xì)菌分類和鑒定的重要性狀。它是1884年由丹麥醫(yī)師Gram創(chuàng)立的。革蘭氏染色法(Gram stain)不僅能觀察到細(xì)菌的形態(tài)而且還可將所有細(xì)菌區(qū)分為兩大類：染色反應(yīng)呈藍(lán)紫色的稱為革蘭氏陽性細(xì)菌，用G+表示；染色反應(yīng)呈紅色(復(fù)染顏色)的稱為革蘭氏陰性細(xì)菌，用G-表示。
細(xì)菌對于革蘭氏染色的不同反應(yīng)，是由于它們細(xì)胞壁的成分和結(jié)構(gòu)不同而造成的。革蘭氏陽性細(xì)菌的細(xì)胞壁主要是由肽聚糖形成的網(wǎng)狀結(jié)構(gòu)組成的，在染色過程中，當(dāng)用乙醇處理時(shí)，由于脫水而引起網(wǎng)狀結(jié)構(gòu)中的孔徑變小，通透性降低，使結(jié)晶紫-碘復(fù)合物被保留在細(xì)胞內(nèi)而不易脫色，因此，呈現(xiàn)藍(lán)紫色；革蘭氏陰性細(xì)菌的細(xì)胞壁中肽聚糖含量低，沒有磷壁酸，其細(xì)胞壁中游肽橋、肽尾和雙糖形成的網(wǎng)狀結(jié)構(gòu)較為疏松，而脂類物質(zhì)含量高，當(dāng)用乙醇處理時(shí)，脂類物質(zhì)溶解，細(xì)胞壁的通透性增加，使結(jié)晶紫-碘復(fù)合物易被乙醇抽出而脫色，然后又被染上了復(fù)染液(番紅)的顏色，因此呈現(xiàn)紅色。

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Cytokeratin LMW(低分子量細(xì)胞角蛋白)

【產(chǎn)品介紹】

細(xì)胞定位：細(xì)胞漿

克隆號：AE1

同型：IgG1

適用組織：石蠟/冰凍

陽性對照：闌尾

抗原修復(fù)：熱修復(fù)（EDTA）

抗體孵育時(shí)間：30-60min

Cytokeratin LMW(低分子量細(xì)胞角蛋白)

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【公司名稱】 廣州健侖生物科技有限公司
【市場部】     歐

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【騰訊  】 
【公司地址】 廣州清華科技園創(chuàng)新基地番禺石樓鎮(zhèn)創(chuàng)啟路63號二期2幢101-103室

This antibody recognizes 56.5, 50.48 and 40 kDa acidic cytokeratins. And vimentin, knot protein, glial fibrillary protein and neurofilament no cross-reaction. Tumor used to mark the epithelial and epithelial origin, in particular, to study whether the metastatic tumor is epithelial derived have some significance.

Gram staining reaction is an important trait of bacterial classification and identification. It was founded in 1884 by Danish physician Gram. Gram stain not only observes the morphology of bacteria but also distinguishes all bacteria into two broad categories: Gram-positive bacteria with a blue-purple staining reaction, denoted by G +, and a red staining reaction (Counterstain color) called Gram-negative bacteria, with G-said.
Bacteria react differently to Gram stains due to the composition and structure of their cell walls. The cell wall of Gram-positive bacteria is mainly composed of a network structure formed by peptidoglycan. In the dyeing process, when treated with ethanol, the pore size in the network structure decreases due to dehydration, and the permeability decreases, The crystal violet-iodine complex is retained in the cell and is not easy to decolorize, therefore, the color is blue-violet; the content of peptidoglycan in the cell wall of Gram-negative bacteria is low and there is no teichoic acid. Disaccharide formation of the network structure is more loose, while the lipid content is high, when treated with ethanol, the lipid material is dissolved, the permeability of the cell wall increases, the crystal violet-iodine complex is easily extracted by ethanol and decolorization, and then They were also dyed with the color of the complex dye solution (saffron) and therefore reddish.